proteinase inhibitors การใช้

• This protein is a member of the serpin superfamily of serine proteinase inhibitors.
• MMP inhibitors could also be administered along with cytotoxic agents or other proteinase inhibitors.
• The proteinase inhibitors interfere with the insect digestive process and discourage the insect from eating the plant again.
• The domains are also seen in the extracellular part of agrins which are not known to be proteinase inhibitors.
• Proteins of the matrix metalloproteinase ( alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
• This inhibition mechanism is common for the majority of serine proteinase inhibitor proteins, and many analogous examples are known.
• Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors.
• MeJA can induce the plant to produce multiple different types of defense chemicals such as phytoalexins ( antimicrobial ), nicotine or proteinase inhibitors.
• A quick approval would give Invirase a head start against Crixivan-- Merck's experimental proteinase inhibitor and Invirase's main competitor.
• The TERF1 gene is also known as TRF, PIN2 ( Proteinase Inhibitor 2 ), TRF1, t-TRF1 and h-TRF1-AS.
• Proteins of the Bowman Birk inhibitor family of serine proteinase inhibitors interact with the enzymes they inhibit via an exposed surface loop that adopts the canonical proteinase inhibitory conformation.
• Due to its cysteine protease structure, Der p 1 may be irreversibly cysteine proteinase inhibitor KCPI1 has also been shown to be able to inhibit Der p 1.
• The transcription of defensive gene produces either proteins that are directly involved in plant defence such as proteinase inhibitors or are enzymes that are essential for the production of such proteins.
• *proteinase inhibitor from the eggs of " Pomacea canaliculata " " ( eggs pictured ) " interacts as a trypsin inhibitor with the protease of potential predators.
• First direct evidence ( of all animals ), that proteinase inhibitor from eggs of " Pomacea canaliculata " interacts as trypsin inhibitor with protease of potential predators, has been reported in 2010.
• The superfamily of high molecular weight serine proteinase inhibitors ( serpins ) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration.
• PAK2 kinase activity is stimulated by transforming growth factor ? in fibroblasts, by proteinase inhibitor alpha2-macroglobulin binding to GRP78 in prostate cancer cells, by its phosphorylation by AMP-activated protein kinase in stem and cancer cells and eryptosis.
• Invirase, also known by the chemical name saquinavir, and other experimental proteinase inhibitors under development by Merck & AMP; Co ., Abbott Laboratories, Agouron Pharmaceuticals and others, have few of the side effects that trouble patients on currently approved AIDS drugs.
• They have succeeded with several proteins, including alpha-1 proteinase inhibitor, for treatment of congenital emphysema and cystic fibrosis; human growth hormone; Factor X, for treating hemophilia; myelin basic protein and beta interferon for multiple sclerosis; and several monoclonal antibodies for treating cancer.
• The introduction of Invirase, and other so-called " proteinase inhibitors " that interfere with reproduction of the virus, could double the market for AIDS drugs and push it over the $ 1 billion mark annually, said Neil Sweig, now an analyst at Brown Brothers Harriman.